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Nicotine in Diseases of Nervous System While neurodegenerative diseases appeared to be more prevalent in smokers than non-smokers, epidemiological studies during the early 1960s provide the first evidence of more smoking is used, less incidence of Parkinsons disease is observed [191, 192]

doi:10.1152/ajplung.00272.2015

[189] [190] Economics In the United States, cigarette smoking is estimated to cost the economy more than $96.8 billion a year in lost productivity from premature death, [191] and more than $225 billion a year in smoking-attributable healthcare spending as of 2014 based on data from 20102014